On The Beam

$15,000 research grant goes to Indiana scientist

The LSA Board of Directors voted in February to award a $15,000 research grant to Bonnie Blazer-Yost, Ph.D., a molecular biologist from Indiana University/Purdue University in Indianapolis, Indiana. The grant, supported entirely by gifts and contributions from LSA friends and members, will come from the newly-named Leland McSpadden Memorial Fund for Medical and Scientific Research on Lowe Syndrome.

The grant will support Blazer-Yost's proposal, entitled "Stable Expression of the OCRL1 Gene in Renal Epithelial Cells: Models for Studying the Localization, Regulation and Metabolic Role of the OCRL1 Protein." This project will be a continuation of Blazer-Yost's studies on the Lowe syndrome enzyme, begun two years ago when she was awarded a previous LSA medical research grant.

One of the goals of the new project is to develop cell lines which can be used by other investigators in the future to help determine the exact role of the Lowe syndrome enzyme in cellular function. One of the reviewers of the proposal stated that Blazer-Yost's experiments "are expected to yield some important insight into the defective mechanisms underlying Lowe syndrome."

The LSA Board of Directors is pleased to be able to fund the new project and is appreciative of all the contributors who helped make it possible.

Winter/Spring 2001, v.20:1

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